Squib is a Ruby DSL for prototyping card and board games
http://squib.rocks & https://github.com/andymeneely/squib
pycard is a card game prototyping engine https://github.com/ghostsquad/pycard
CardPen generates simple HTML pages of cards for printing up yourself, or it can convert your HTML cards to PNG images at any DPI for uploading to card printing services that accept image files http://cardpen.mcdemarco.net/doc/index.html
HCCD is a small tool designed to automate the creation of game cards from a CSV (Excel) file using a few lines of HTML and CSS. https://github.com/vaemendis/hccd/